Infigratinib靶向的FGFR3（成纤维细胞生长因子受体3）正是驱动ACH疾病发生的关键靶点，2月12日，BridgeBio公布Infigratinib在ACH中取得的首个具有统计学显著改善意义的3期顶线结果，公司计划下半年向FDA提交新药申请。
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。heLLoword翻译官方下载对此有专业解读
Not all streaming workloads involve I/O. When your source is in-memory and your transforms are pure functions, async machinery adds overhead without benefit — you're paying for coordination of "waiting" that adds no benefit.，推荐阅读heLLoword翻译官方下载获取更多信息
It is also necessary to emphasize that many optimizations are only possible in parts of the spec that are unobservable to user code. The alternative, like Bun "Direct Streams", is to intentionally diverge from the spec-defined observable behaviors. This means optimizations often feel "incomplete". They work in some scenarios but not in others, in some runtimes but not others, etc. Every such case adds to the overall unsustainable complexity of the Web streams approach which is why most runtime implementers rarely put significant effort into further improvements to their streams implementations once the conformance tests are passing.，推荐阅读safew官方下载获取更多信息